The Cast of ‘Frasier’: Where Are They Now?

Kelsey Grammer as Dr. Frasier Crane

Grammer joined the cast of Cheers early in his career — 1984, to be exact — growing his slightly neurotic psychiatrist Dr. Frasier Crane from Boston barfly to Seattle radio host on the 1993 spinoff, Frasier.

He won three Emmys for his work, and hasn’t slowed down since, voicing Sideshow Bob on The Simpsons, starring in several Broadway productions and even joining daughter Spencer in a 2022 Lifetime holiday movie.

The actor — who has been touched by tragedy through the years, between murders that took his sister and father and a suspected shark attack that killed his step-brothers — is a father of seven kids, spanning ages 6 to 39, and has been married to fourth wife Kayte Walsh since 2011.

Grammer, 68, will return for the Frasier revival, premiering in October 2023.

David Hyde Pierce as Dr. Niles Crane

Pierce had dabbled in TV and movies before joining the cast of Frasier as the doc’s younger brother, Niles, also a psychiatrist.

“If I turn on the television I’ll happen on it and I’m always impressed by how they hold up,” the four-time Emmy winner told Katie Couric in 2013. “It’s about the writing more than anything else, the writing was so good, and wasn’t too tied into specific events of the period. You get used to the clothes and the size of the portable phones. But people tell me all the time they’re still laughing at it and that’s a nice thing.”

Though he isn’t returning for the revival — Grammer said Pierce “wasn’t really interested in repeating the performance” — he has been quite busy in the years since Frasier ended, starring in several Broadway productions and more recently as Julia Childs’ husband Paul in HBO Max’s Julia. Like Grammer, he did voice work on The Simpsons, too.

The two-time Tony Award winner, 64, has been with his husband, Brian Hargrove, for 40 years.

Jane Leeves as Daphne Moon

Leeves had roles on Seinfeld, Murphy Brown and Throb before joining Frasier as patriarch Martin Crane’s witty live-in caretaker — and eventual Mrs. Niles Crane.

As the series wound down, she followed in her costars’ footsteps, going to Broadway for a stint as Sally Bowles in Cabaret. She later struck TV gold once again on the sitcom Hot in Cleveland, alongside Valerie Bertinelli, Wendie Malick and Betty White.

Leeves, 62, has two children with her husband, television executive Marshall Coben.

Peri Gilpin as Roz Doyle

Gilpin had a string of TV shows under her belt — most notably Flesh ‘n’ Blood — when she landed the role of Frasier’s colleague Roz on Frasier (a role that almost went to Lisa Kudrow!).

And like her costars, she has stayed busy on the small screen ever since, picking up voice work in addition to parts on Scorpion, Make It or Break It and Mrs. Robinson, which also starred Grammer’s daughter, Spencer.

The actress, 62, will return to the Frasier revival as a guest star.

Gilpin is married with two children.

Bebe Neuwirth as Dr. Lilith Sternin

Coming with Grammer from Cheers was Neuwirth, who played Lilith, his icy ex and mother of his child.

She got her start on stage, featuring in A Chorus Line, Dancin’, Little Me and Sweet Charity before Frasier took off. A two-time Tony winner, she returned to Broadway after the series, in shows including Damn Yankees, Fosse, Funny Girl, Chicago and The Addams Family, though has kept up with TV and movie work too, on Deadline, Madam Secretary and in How to Lose a Guy in 10 Days.

She’ll also return to the Frasier revival in a guest starring role, it was confirmed earlier this year.

Neuwirth, 64, has been married to second husband Chris Calkins since 2009.

John Mahoney as Martin Crane

Mahoney got his start on the Chicago stage, joining the storied Steppenwolf Theatre after immigrating from England.

“The theater is my brothers, my sisters, my father, my mother, my wife,” he once said. “It is everything to me.”

His Emmy-nominated work as Niles and Frasier’s retired dad was his most notable TV role, though he did appear on several episodes each of In Treatment and Leeves’ Hot in Cleveland, in addition to voicing a Simpsons character with his TV sons.

He eventually returned to stage work, though, starring in the Broadway revival of the play Prelude to a Kiss, Better Late and The Outgoing Tide at the Northlight Theatre in Illinois.

The actor — who never married and did not have children — died in 2018 at age 77.

Moose as Eddie

As much of a character as any of the humans on the series, pup Eddie — played by Jack Russell terrier Moose — lived a long life, dying in 2006 at age 16. He was “extremely mischievous,” trainer Mathilde Halberg told PEOPLE at the time.

The dog also portrayed Skip in the 2000 film, My Dog Skip.